Headache and Pain Research

Update on Cluster Headaches: From Genetic to Novel Therapeutic Approaches: Myun Kim, Je Kook Yu, Yoo Hwan Kim; Headache Pain Res. 2024;25(1):42-53. Published online April 22, 2024; DOI: https://doi.org/10.62087/hpr.2024.0009

Abstract PDF: Cluster headaches affect 0.1% of the population and are four times more common in males than in females. Patients with this condition present with severe unilateral head pain localized in the frontotemporal lobe, accompanied by ipsilateral lacrimation, conjunctival injection, nasal congestion, diaphoresis, miosis, and eyelid edema. Recently, the first genome-wide association study of cluster headaches was conducted with the goal of aggregating data for meta-analyses, identifying genetic risk variants, and gaining biological insights. Although little is known about the pathophysiology of cluster headaches, the trigeminovascular and trigeminal autonomic reflexes and hypothalamic pathways are involved. Among anti-calcitonin gene-related peptide monoclonal antibodies, galcanezumab has been reported to be effective in preventing episodic cluster headaches.

Update on Treatment of Giant Cell Arteritis: Mi-Kyoung Kang, Yoo Hwan Kim, Kyeong Min Son, Soo-Jin Cho , Jiyoung Kim, Jong-Hee Sohn, On behalf of the Hallym Headache Research Society; Published online December 31, 2022

Crowned Dens Syndrome Mimicking Meningitis: Na Hee Kim, Myun Kim, Chaery Jeon, Yoo Hwan Kim; Published online June 30, 2022

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